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However, with inefficient metabolism or excess glucose in the bloodstream, this is either stored for later use as glycogen or remains in the bloodstream, which results in "sugar spikes" and ultimately adverse effects.Prime Lean boasts a cutting-edge formulation of Dihydroberberine, as GlucoVantage®, that is shown to be 5x more effective vs normal berberine), bitter melon, and cinnamon extract.Whether you are looking to optimize your longevity, manage blood glucose levels after a cheat or carb-rich meal, increase your caloric intake without the negative effects on insulin, or just looking to lose weight, Prime Lean is the perfect solution! Prime Lean is best used before meals (particularly carbohydrate-rich meals) to prime the body for optimal insulin management.